Monoclonal antibodies are made in a laboratory and may help our bodies fight the virus that causes COVID-19 . They are given to patients directly with an infusion or a shot.

The FDA has issued Emergency Use Authorizations (EUAs) for a number of investigational monoclonal antibodies.

Monoclonal Antibody Therapy Frequently Asked Questions

Updated on April 12, 2022

  • There are several different types of monoclonal antibody products.

    Each antibody product targets specific variants and sub-variants of the COVID-19 virus.

    Under the FDA’s EUA, we can use monoclonal antibody products that target the dominant strain in our area. The dominant strain in Florida as of early April 2022 is Omicron sub-variant BA.2.

    Bebtelovimab (from Eli Lilly) is currently authorized by an FDA EUAfor the treatment of mild-moderate COVID-19, including infection caused by Omicron sub-variant BA.2

    Tixagevimab/cilgavimab (Evusheld from AstraZenica) is currently authorized by an FDA EUA for pre-exposure prophylaxis (prevention) of COVID-19, including infection caused by Omicron sub-variant BA.2.

    Previous SARS-CoV-2 monoclonal antibody products including bamlanivimab/etesevimab (from Eli Lilly), casirivimab/imdevimab (REGEN-COV from Regeneron), and sotrovimab (Xevudy from GlaxoSmithKline) are no longer authorized for use in the United States due to lack of adequate activity against Omicron sub-variant BA.2.

  • Baptist health is offering bebtelovimab to patients who meet criteria for this therapy.

    Patients who believe they may meet the criteria for bebtelovimab should go to a Baptist Health Urgent Care location to be evaluated by a medical professional. Patients who meet criteria will be referred and scheduled for the treatment.

  • Patients must be evaluated by a medical professional at a Baptist Health Urgent Care Center location in order to be referred for the treatment at a Baptist Health location.

  • There are two oral therapies available at some community pharmacies. They are nirmatrelvir/ritonavir (Paxlovid from Pfizer) and molnupiravir (Lagevrio from Merck). Locations that carry these therapies can be found using this government tracker website. Your provider should determine which (if any) of the COVID therapies are best for you.

  • Having full vaccination with a COVID-19 vaccine and the appropriate booster helps to increase your protection against COVID-19. For more information about vaccine boosters, click here.